This brief presents findings from key informant interviews conducted as part of the Early Childhood Systems Collective Impact Project. The project seeks to improve health and well-being and promote equitable outcomes for expectant parents, young children (birth to age 8), and their families by re-envisioning an aligned and coordinated approach for federal programs and policies that serve them. The purpose of the key informant interviews was to understand barriers at the federal, state, tribal, and local levels that impede the development of coordinated, comprehensive early childhood systems; learn about promising efforts to overcome those barriers; and inform recommendations for future action. (author abstract)